Gut health

A healthy gut as a major asset against many pathologies

 

Gastro-intestinal health and the maintenance of a balanced microflora is the first field of application for probiotics, both historically and in scientific evidence.

Today, the efficiency of probiotics in this domain is not widely accepted but supported by many experts and health practitioners.

By selecting strains that exert different and complementary activities, it is possible to formulate specific probiotics for targeted digestive applications.

Certain strains show complementary modes of action or effects and their combination can help offer optimal efficacy for one specific indication or even multiple benefits for a more generic indication such as microflora balance, diarrhea prevention (antibiotic associated, traveller’s or acute diarrhea…), IBS symptoms and lactose intolerance.

 Lallemand Health Solutions has developed custom-tailored and ready-to-market formulas for Gastro intestinal Range :

  • Lacidofil®: Probiotic blend with Lactobacillus rhamnosus Rosell-11 and Lactobacillus helveticus Rosell-52
  • S.boulardii: Yeast Saccharomyces cerevisiae variant boulardii CNCM I-1079, Premium quality S. boulardii produced in its GMP Pharma certified yeast plant based in Vienna, Austria can be provided as an Active Pharmaceutical Ingredient (API), for the development of registered drugs (according to the country’s regulation).

  • PR-Probiotic 2.0: a clinically documented optimal combination of Saccharomyces boulardii probiotic with Lactobacillus rhamnosus Rosell-11 and Bifidobacterium longum Rosell-175, Probiotic 2.0 have a synergetic effect on travelers’ diarrhea and rotavirus-induced diarrhea in children.

  • Protecflor®:Probiotic blend with Saccharomyces boulardii probiotic yeast, with three specific probiotic bacteria strains: Lactobacillus rhamnosus Rosell-11, Lactobacillus helveticus Rosell-52, and Bifidobacterium longum Rosell-175
    Either alone or in combination, these three probiotic bacteria have also been documented for their effectiveness in protecting the gut and restoring a balanced microflora. While exhibiting different modes of action in the gut, probiotic yeast and bacteria are complementary and allow for dual protection of the gut surface against pathogens

  • Lafti® L10Lactobacillus helveticus Lafti® L10  is effective to improve digestive comfort and offer an overall feel-good sensation, as shown in a randomized placebo-controlled clinical study (cross-over design) (Welin, 2005).

  • Gastro AD®: Food supplement based on non-GMO soy fermented by Lactobacillus  delbrueckii Rosell-187, with excellent track-record of safe and effective use for gastric comfort and the relief of occasional heartburn.


Glossary

The Lactobacillus genus encompasses more than 25 species and includes a diverse range of organisms. These organisms are strictly fermentative, aerotolerant or anaerobic and have complex nutritional requirements. Using glucose as a carbon source, lactobacilli are either homofermentative (more than 85% of their formulation is of lactic acid) or heterofermentative (production of lactic acid, carbon dioxide, ethanol or acetic acid).

Main characteristics:

  • Maintain a healthy and balanced intestinal microbiota and reduce the incidence of intestinal infections.
  • Are often recommended for the prevention of intestinal microbiota problems and diarrhea related to antibiotic treatment.

Contribute to the modulation of specific and non-specific immune defenses.

The Bifidobacterium genus is gram-positive, anaerobic and often ramified. It is the predominant bacterial group in the intestinal flora of healthy newborns that are breastfed, representing more than 95% of all bacteria present. However, the number of these organisms diminishes with time (starting from weaning) to eventually represent an average of 25% of a healthy individual’s intestinal flora.

Main characteristics :

Several studies have clearly identified that bifidobacteria can be effective in the prevention and reduction of diarrheas related to antibiotic treatment or resulting from the rotavirus in children. Anaerobic bacteria belonging to the Bifidobacteria sub-family are also beneficial for the well-being of the host, both during childhood and in later stages of life.
Moreover, they contribute to the modulation of specific and non-specific immune defenses.

Saccharomyces boulardii is a wild tropical yeast that was discovered in Asia in 1923 by the French scientist, Henri Boulard. Boulard succeeded in isolating it from the peel of various tropical fruits (lychees, mangosteens) after having observed that indigenous populations were using the peels of such fruit as antidiarrheals.
Saccharomyces boulardii is the only probiotic yeast. It has been used for decades in Europe and belongs to the same family as Saccharomyces cerevisiae but differs on the genetic, metabolic and physiological levels. It is unicellular and globular, and it reproduces by budding, which leaves scars on its surface.

Main Characteristics:

  • Prevents and treats diarrheas related to antibiotic treatment
  • For maintenance and reestablishment of GIT microflora
  • For prevention of travel diarrhea
  • Treats diarrhea in children