Immunity

Immunity is a basic condition for health at any period of life

 The interactions between probiotics and immunity are increasingly well understood. Thanks to a strong research program dedicated to immunity, encompassing innovative in vitro, in vivo and clinical studies, scientists at Lallemand Health Solutions are now able to draw a better picture of the pathways involved and the clear benefits of selected probiotic strains.

On this basis, we have been able to design a portfolio of probiotic strains to address various issues of immune health for different target groups: children, adults or seniors.

poster immunity

Children

Their immune system is maturing and children are at higher risk of infections or atopic disorders (Th2 reaction). Young children are prone to colds and may have 8 to 12 of them every year. Atopic dermatitis usually starts within the first six months of life and its prevalence is 14% among children under four.

Adults

In healthy adults, common infections such as cold and flu can be frequent and contagious, particularly during winter or at the seasonal transitions. Adults get an average of two to four colds per year, mostly between September and May. In addition,  chronic stress and high intensity exercise increase the risk of common infections due to an immunosuppressive effect. Thus, populations exposed to high degrees of physical and environmental stress, such as sportsmen and daily-life stressed people, may suffer from an increased incidence of upper respiratory tract illness.

Seniors

The elderly are more susceptible to infectious diseases such as influenza, which can deteriorate into more serious conditions such as pneumonia. There is a strong body of evidence showing that aging is accompanied by severe alterations in the immune system. This is called immunosenescence.

 

 

  •  Lactobacillus helveticus Rosell-52
  • Bifidobacterium infantis Rosell-33
  • Bifidobacterium bifidum Rosell-71
  • Lactobacillus rhamnosus Rosell-11
  • Bifidobacterium longum Rosell-175
  • Lactobacillus rhamnosus Rosell-343
  • Lactobacillus rhamnosus HA-111
  • Lactobacillus brevis HA-112
  • Bifidobacterium infantis HA-116
  • Lactobacillus fermentum HA-179
  • Lactobacillus reuteri HA-188
  • Lactobacillus paracasei HA-196
  • Lactobacillus helveticus Lafti L10
  • Lactobacillus paracasei Lafti L26
  • Bifidobacterium lactis Lafti  B94
  • Saccharomyces boulardii

See which proprietary probiotic strains are selected for their potential applications areas :

Lallemand Health Solutions proprietary probiotic strains with their potential applications areas in Immunity for children (relevance rating from + to +++ for the highest)

PRO176-LB-IM.indd

Lallemand Health Solutions proprietary probiotic strains with their potential applications areas in Immunity for adults  (relevance rating from + to +++ for the highest)

PRO176-LB-IM.indd

Lallemand Health Solutions proprietary probiotic strains with their potential applications areas in Immunity for seniors  (relevance rating from + to +++ for the highest)

PRO176-LB-IM.indd

 

All of our strains in Lallemand Health Solutions’ collection have been clearly identified and documented based on their principal properties and health Benefits.

Reliable Strains

Having conducted extensive research over the past 80 years, Lallemand Health Solutions has assured its strains are safe for human consumption. Today, the company’s commitment to safety is as firm as ever, and it continues to focus particular attention on such areas as genome decryption, resistance to antibiotics, and in vivo toxicological studies, among others.

 Stable Strains

Lallemand Health Solutions’ strains are carefully selected not only for their health benefits, but also for their ability to survive through their arrival at their action site. In that regard, the company has developed an ongoing research program for improving the production and formulation of its products in order to provide the organism with the number of bacteria it needs, where it needs them.

Documented Strains

Lallemand Health Solutions scientifically documents its strains internally, but also through its numerous partnerships with the scientific community.

Strains Innovations

Some of our strains have been pushed in the R&D process, and can be offered in different versions :

  • Non Dairy strains (ND)
  • Probiocap® Microencapsulated strains (ME)

 


 

Glossary

The Lactobacillus genus encompasses more than 25 species and includes a diverse range of organisms. These organisms are strictly fermentative, aerotolerant or anaerobic and have complex nutritional requirements. Using glucose as a carbon source, lactobacilli are either homofermentative (more than 85% of their formulation is of lactic acid) or heterofermentative (production of lactic acid, carbon dioxide, ethanol or acetic acid).

Main characteristics:

  • Maintain a healthy and balanced intestinal microbiota and reduce the incidence of intestinal infections.
  • Are often recommended for the prevention of intestinal microbiota problems and diarrhea related to antibiotic treatment.
  • Contribute to the modulation of specific and non-specific immune defenses

The Bifidobacterium genus is gram-positive, anaerobic and often ramified. It is the predominant bacterial group in the intestinal flora of healthy newborns that are breastfed, representing more than 95% of all bacteria present. However, the number of these organisms diminishes with time (starting from weaning) to eventually represent an average of 25% of a healthy individual’s intestinal flora.

Main characteristics :

Several studies have clearly identified that bifidobacteria can be effective in the prevention and reduction of diarrheas related to antibiotic treatment or resulting from the rotavirus in children. Anaerobic bacteria belonging to the Bifidobacteria sub-family are also beneficial for the well-being of the host, both during childhood and in later stages of life.

Moreover, they contribute to the modulation of specific and non-specific immune defenses.

 

 

Saccharomyces boulardii is a wild tropical yeast that was discovered in Asia in 1923 by the French scientist, Henri Boulard. Boulard succeeded in isolating it from the peel of various tropical fruits (lychees) after having observed that indigenous populations were using the peels of such fruit as antidiarrheals. Saccharomyces boulardii is the only probiotic yeast. It has been used for decades in Europe and belongs to the same family as Saccharomyces cerevisiae but differs on the genetic, metabolic and physiological levels. It is unicellular and globular, and it reproduces by budding, which leaves scars on its surface.

Main Characteristics:

  • Prevents and treats diarrheas related to antibiotic treatment
  • For maintenance and reestablishment of GIT microflora
  • For prevention of travel diarrhea
  • Treats diarrhea in children

 

Lallemand Health Solutions has developed custom-tailored and ready-to-market formulas for Immunity Range :

 

Probiokid® and Probiostim®: Blend with a prebiotic (FOS) and three specific probiotic strains Lactobacillus helveticus Rosell-52, Bifidobacterium bifidum Rosell-71, Bifidobacterium infantis Rosell-33: selected for their ability to stimulate the specific and non-specific immune system. This combination is highly recommended to help balance de microflora, essential to the body’s natural defences. Probiokid’s formulation is packaged under sachet, adressing to children and Probiostim is packaged in blister caps targeting adults and seniors market.

Lafti® L10 : Lactobacillus helveticus Lafti® L10
supported by several clinical studies in immune support, backed by in vitro and in vivo evidences of its modes of action and immunomodulating abilities, in restoring the depressed immune response of fatigued athletes (Clancy, 2006) . This well-studied and characterized strain shows good probiotic characteristics including adherence to gut epithelial cells, survival in the intestinal tract and promotion of pathogen clearance.

 


Glossary

The Lactobacillus genus encompasses more than 25 species and includes a diverse range of organisms. These organisms are strictly fermentative, aerotolerant or anaerobic and have complex nutritional requirements. Using glucose as a carbon source, lactobacilli are either homofermentative (more than 85% of their formulation is of lactic acid) or heterofermentative (production of lactic acid, carbon dioxide, ethanol or acetic acid).
Main characteristics:

  • Maintain a healthy and balanced intestinal microbiota and reduce the incidence of intestinal infections.
  • Are often recommended for the prevention of intestinal microbiota problems and diarrhea related to antibiotic treatment.
  • Contribute to the modulation of specific and non-specific immune defenses.

The Bifidobacterium genus is gram-positive, anaerobic and often ramified. It is the predominant bacterial group in the intestinal flora of healthy newborns that are breastfed, representing more than 95% of all bacteria present. However, the number of these organisms diminishes with time (starting from weaning) to eventually represent an average of 25% of a healthy individual’s intestinal flora.

Main characteristics :

Several studies have clearly identified that bifidobacteria can be effective in the prevention and reduction of diarrheas related to antibiotic treatment or resulting from the rotavirus in children. Anaerobic bacteria belonging to the Bifidobacteria sub-family are also beneficial for the well-being of the host, both during childhood and in later stages of life.

Moreover, they contribute to the modulation of specific and non-specific immune defenses.